Quick Summary Moderna and Merck’s experimental personalized cancer vaccine (mRNA‑based) plus an immune checkpoint inhibitor showed long‑term benefit in high‑risk melanoma. Five‑year Phase 2b data (KEYNOTE‑942) showed the combination reduced the risk of distant spread by 59%, lowered recurrence or death risk by 49%, and improved overall survival (92.2% vs
Quick Summary A new investigational targeted therapy (setidegrasib) targets the KRAS G12D mutation, common in pancreatic cancer and some lung cancers. In a phase 1 clinical trial of 203 patients, objective response rate was 36% for non-small cell lung cancer and 24% for pancreatic cancer. The drug helps cancer cells
Quick Summary A Phase II clinical trial presented at AACR 2026 found that long-term immunotherapy with atezolizumab may be safe for alveolar soft part sarcoma (ASPS) patients beyond the traditional 2-year window. Among 17 patients treated for over 2 years (up to 5+ years), only 3 experienced moderate side effects,
Quick Summary Emerging therapies for hard-to-treat uterine cancer include targeted therapy, hormonal therapy, immune checkpoint inhibitors, and radiation therapy. These options help patients with advanced or recurrent endometrial cancer, especially when standard treatments don’t work. Targeted therapy: Attacks specific features of tumor cells while sparing healthy tissue Immune checkpoint inhibitors:
Quick Summary Scientists have engineered probiotic bacteria (E. coli Nissle 1917) to locate tumors and produce the cancer drug romidepsin directly inside the tumor microenvironment. In mouse models, this approach slowed tumor growth and may offer a more precise targeted therapy with fewer side effects than traditional chemotherapy. How it
Summary Cervical cancer remains a global health challenge, with many patients diagnosed at advanced stages. Standard treatment combines external beam radiotherapy with brachytherapy. Image-guided adaptive brachytherapy using MRI or CT scans represents a major advancement, allowing physicians to deliver higher radiation doses directly to tumors while protecting nearby organs at
Quick Overview: Cold Spring Harbor Laboratory scientists discovered how treatment-resistant pancreatic and lung cancers evade therapy by changing cell identity. By targeting molecular switches, KLF5 in pancreatic cancer and POU2F3/OCA-T1 in lung cancer, researchers found new ways to stop tumor growth. The Problem: Cancer cells “shapeshift” between identities to survive
Summary Breast cancer affects millions of women worldwide. Many patients ask whether they can treat breast cancer without surgery. Doctors now offer non-surgical options such as hormone therapy, chemotherapy, and targeted therapies depending on cancer type and stage. Main Focus: Explore non-surgical treatment options for breast cancer. Key Treatment Methods:
Quick Summery A recent study published in 2025 finds that cancer patients who quit smoking within six months of their diagnosis gain nearly one additional year of life. This finding challenges the misconception that quitting after cancer diagnosis is ineffective. The survival benefit applies to all cancer types and stages,
Precision Medicine, AI, and Global Collaboration in Cancer Care Take Center Stage in Berlin Dr. Christina Ng Van Tze, a respected Consultant Medical Oncologist and Medical Director at Onco Life Centre in Bangsar South, Kuala Lumpur, recently represented Malaysia at the ESMO Congress 2025 in Berlin. The global event brought
