
Researchers Crack Treatment-Resistant Pancreatic and Lung Cancers
Quick Overview: Cold Spring Harbor Laboratory scientists discovered how treatment-resistant pancreatic and lung cancers evade therapy by changing cell identity. By targeting molecular switches, KLF5 in pancreatic cancer and POU2F3/OCA-T1 in lung cancer, researchers found new ways to stop tumor growth. The Problem: Cancer cells “shapeshift” between identities to survive














