Quick Summary Moderna and Merck’s experimental personalized cancer vaccine (mRNA‑based) plus an immune checkpoint inhibitor showed long‑term benefit in high‑risk melanoma. Five‑year Phase 2b data (KEYNOTE‑942) showed the combination reduced the risk of distant spread by 59%, lowered recurrence or death risk by 49%, and improved overall survival (92.2% vs
Quick Summary Cervical cancer recurrence happens when microscopic cancer cells survive treatment or the cancer returns later. Signs include pelvic/lower back pain, unusual bleeding, fatigue, or leg swelling. Treatment options include radiation therapy, chemotherapy, or surgery (pelvic exenteration). Regular follow-up with blood tests and imaging scans improves early detection and
Quick Summary Uterine cancer treatment in Malaysia is available at specialist-led oncology centers offering surgery, chemotherapy, and radiation therapy. Early diagnosis improves outcomes. Patients should seek care from gynecologic oncologists who provide structured treatment plans, follow-up monitoring, and supportive care for better recovery and quality of life. Main treatments: Surgery,
Quick Summary Merck’s sac-TMT (anti-TROP2 antibody-drug conjugate) improved overall survival and progression-free survival in advanced or recurrent endometrial cancer after prior platinum chemotherapy and immunotherapy, according to Phase 3 TroFuse-005 trial (N=776). The drug also improved response rate compared to standard chemotherapy. Safety profile consistent with earlier studies. Exact survival
Quick Summary High-dose biotin (vitamin B7) supplements, often found in hair, skin, and nails products, can interfere with lab tests used to monitor prostate, thyroid, ovarian, and breast cancer. Biotin can cause falsely high or low results by disrupting chemical reactions in certain assays. Patients should tell their oncology team
Quick Summary A new liquid biopsy method (not yet ready for routine care) analyzes immune-related signals in blood to predict which breast cancer patients may benefit from immunotherapy. In a study of stage 2-3 HER2-negative breast cancer patients (546 blood samples from 160 patients), blood transcriptomic patterns linked T-cell activity
Quick Summary Persistent ear blockage or hearing loss (especially one-sided) may sometimes be linked to nasopharyngeal cancer (NPC), a cancer in the upper throat behind the nose. The tumor can block the Eustachian tube, causing fluid buildup and hearing changes. Other warning signs include neck lump, nose blockage, nosebleeds, or
Quick Summary Oncologists guide cancer survivors after treatment by creating structured survivorship care plans, monitoring for recurrence, managing long-term side effects, and coordinating with primary care. Survivorship care includes follow-up schedules, risk monitoring, emotional support, and lifestyle guidance. This ongoing support improves safety, quality of life, and long-term health outcomes.
Quick Summary Some colon polyps (adenomatous, serrated) can turn into colorectal cancer over 5-10 years. Most polyps cause no symptoms. Colonoscopy starting at age 45 detects and removes polyps safely, preventing cancer. Types: Adenomatous (pre-cancerous), serrated (higher risk), hyperplastic (harmless) Risk factors: Age 45+, family history, IBD, genetics, smoking, poor
Quick Summary Bone metastasis occurs when breast cancer spreads to bones (spine, pelvis, ribs, limbs), classified as stage IV breast cancer. Key symptoms include persistent bone pain, fractures from minor injuries, limited mobility, numbness, and fatigue. Treatment options: radiation therapy (pain relief, fracture prevention), hormone therapy, targeted therapy, pain medications,
